More thanВ 1.25 million people suffer from type 1 diabetes in the US. The latest researches shows that aВ vaccineВ for tuberculosis (bacillus Calmette-Guerin), which is already used for more than 100 years, canВ reversing the diabetes. This vaccine is considered as safe and it is alsoВ usedВ for treating bladder cancer.
At the 75th Scientific Sessions of the American Diabetes Association it was said that this vaccine is going to be tested by the FDA. They will do the test onВ 150 people who are in an advanced stage of type one diabetes.
This vaccine is able to eliminate the T cells. This cells are produced in the bodyВ who hasВ type 1 diabetes and theyВ create problems in the pancreatic islets, where the insulin is created.
It was found thatВ the patients with diabetes who were already injected with this vaccine,В destroys the T cells that are hindering the production of insulin. After a four weeksВ of injection,В the dangerous T cells were gone. The patients were injected twice a day and theyВ began to secrete insulin on their own.
вЂњIn the phase I (preliminary) trial we demonstrated a statistically significant response to BCG, but our goal in (this trial) is to create a lasting therapeutic response. We will be working again with people who have had type 1 diabetes for many years. This is not a prevention trial; instead, we are trying to create a regimen that will treat even advanced disease.вЂќ – saidВ Dr. Denise Faustman, director of the Massachusetts General Hospital Immunobiology Laboratory in Boston.
This summer the vaccine will be tested on 150 people with differentВ range in ages, from 18 to 60В years old. The trial will be done in the sameВ format as was used before by injecting patients, twice a day within a four-week period.
There are some experts who doesn’t believe that theВ treatment will work.
вЂњI think itвЂ™s a stretch to say this would have a huge impact on the millions plus type I diabetes patients in this country. We would love to do something to preserve or repopulate their beta cell mass. Historically, we have watched it dwindle and have not been able to do something (in time).вЂќ – saidВ Robert Sobel, an assistant professor of endocrinology at Northwestern UniversityвЂ™s Feinberg School of Medicine.
The time will show if the vaccineВ will become a proven cure in treatingВ type 1 diabetes or not.